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A subset of patients find that their body's response plateaus on tirzepatide after initial success, or they achieve their goal weight and seek a maintenance-phase medication with potentially milder side effects

In lower doses, hunger suppression may not noticeably last for a whole week, even though the medication may still work in other ways

Directing a stream of water at them creates hydraulic force that can physically shear the peptide bonds apart

[1] That is the central clinical point

Smoking was defined as smoking at least one cigarette or equivalent daily